Overdosage of cholestyramine resin has become noted inside a affected person using a hundred and fifty% of the utmost advisable daily dosage for any period of numerous weeks. No unwell results ended up described.

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Cholestyramine resin might interfere With all the pharmacokinetics of drugs that bear enterohepatic circulation. The discontinuance of cholestyramine resin could pose a hazard to health if a most likely harmful drug which include digitalis has been titrated to the servicing level even though the patient was having cholestyramine resin.

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Having said that, in watch of The reality that cholestyramine resin is confined to the GI tract instead of absorbed and in gentle of your animal experiments referred to previously mentioned, a six-year put up-demo stick to-up from the LRC-CPPT5 client inhabitants has become completed (a complete of 13.4 yrs of in-demo furthermore article-demo abide by-up) and discovered no substantial big difference during the incidence of bring about-unique mortality or most cancers morbidity among cholestyramine and placebo treated clients.

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One affected individual seasoned biliary colic on each of a few events on which he took a cholestyramine for oral suspension product. One patient diagnosed as acute abdominal symptom intricate was found to possess a “pasty mass” while in the transverse colon on x-ray.

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